speCTraMet is organised into six work packages. Four technical work packages (WP1–WP4) deliver the core research; one impact work package (WP5) ensures results reach the right communities; and one management work package (WP6) coordinates the consortium throughout the 36-month programme.
Work Packages
WP1 — Anthropomorphic Reference Standard Phantoms
- Lead: Jacco de Pooter, VSL
- Objectives: Develop experimental methods to characterise physical sCT reference phantoms with traceable, energy-binned linear attenuation coefficients at 1% target uncertainty. Build validated virtual (digital) twins of the physical phantoms for uncertainty and sensitivity analysis.
- Tasks:
- Task 1.1: Literature review of equipment used in sCT
- Task 1.2: Physical reference phantoms
- Task 1.3: Development of virtual phantoms
- Task 1.4: Sensitivity analysis and uncertainty assessmentManagement plans, periodic and final reports
- Key outputs:
- D1: Methodologies to measure traceable energy-binned linear attenuation coefficients (M21)
- D2: Methodology to assess uncertainties of sCT measured HUs using virtual phantoms (M33)
WP2 — Imaging Biomarker Uncertainty Assessment and Variability Reduction in a Multisystem Study
- Lead: Marcel van Straten, Erasmus MC
- Objectives: Select clinically relevant sCT imaging biomarkers, configure an anthropomorphic phantom using WP1 inserts, and conduct a systematic multi-vendor, multi-centre variability study. Produce harmonised guidance and protocols for clinical and multicentre use.
- Tasks:
- Task 2.1: Imaging biomarker selection and anthropomorphic phantom setup
- Task 2.2: Multisystem study preparation
- Task 2.3: Multisystem study
- Task 2.4: Guidance on uncertainty assessment and variability reduction
- Key outputs:
- D3: Variability in measuring imaging biomarkers: a multisystem study (M35)
- D4: Guidelines on variability assessment, correction, and harmonised protocols for multicentre studies (M35)
WP3 — Spectral Characterisation of CT X-ray Radiation Beams
- Lead: Jaroslav Solc, CMI
- Objectives: Adapt x-ray spectrometry to characterise energy distributions of CT radiation fields. Define and establish new reference radiation qualities at metrology laboratories, enabling traceable dosimetry for sCT. Generate a validated catalogue of sCT-specific x-ray spectra.
- Tasks:
- Task 3.1: New reference radiation qualities relevant to current CT practice
- Task 3.2: In-beam x-ray spectrometry of clinical CT devices
- Task 3.3: EURAMET pilot comparison study for in-beam x-ray spectrometry
- Task 3.4: Monte Carlo simulations
- Key outputs:
- D5: Catalogue of in-beam x-ray fluence spectra emitted by clinical CT devices (M36)
- D6: Report on the inter-laboratory comparison of in-beam x-ray spectrometry (M24)
WP4 — AI Patient Dosimetry
- Lead: Irida Shallari, MIUN
- Objectives: Deliver a validated AI framework for patient-specific organ dose calculation in sCT. Covers organ segmentation, personalised dose computation, and full uncertainty evaluation aligned with international metrology guidance, tested in a multi-centre clinical validation study.
- Tasks:
- Task 4.1: Framework modelling for AI-based sCT organ segmentation
- Task 4.2: AI for personalised dosimetry in sCT
- Task 4.3: Validation of AI models for dosimetry and organ segmentation
- Key outputs:
- D7: Prototype software framework for personalised sCT dosimetry — open source, with deployment-ready APIs (M36)
- D8: Technical report on end-to-end uncertainties of the AI dosimetry pipeline with GUM-aligned uncertainty budget (M36)
WP5 — Creating Impact
- Lead: Dimitris Visvikis, EFOMP
- Objectives: Ensure all project outputs reach standards bodies, clinicians, metrology laboratories, manufacturers, and the public. Manage dissemination, open-access publishing, stakeholder engagement, and exploitation of results into IEC and IAEA standards processes.
- Tasks:
- Task 5.1: Dissemination and communication
- Task 5.2: Exploitation and uptake
- Key outputs:
- Stakeholder Committee established (M3)
- D1, D5, D6 submitted to IEC TC 62 for updates to IEC 61267 and IEC 61674
- D7 published as open-source software
WP6 — Management and Coordination
- Lead: Stefan Pojtinger, PTB
- Objectives: Provide effective day-to-day coordination, financial management, risk oversight, and reporting for the full 36-month project. Operate a project management board with one representative per beneficiary.
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- Task 6.1: Project management
- Task 6.2: Project meetings
- Task 6.3: Project reporting
- Key outputs:
- Kick-off, mid-term, and final project meetings
- All periodic and final reports submitted to EURAMET
